| Calculation of Filing Fee Tables | |||
| S-1 | |||
| Jaguar Health, Inc. | |||
| Table 1: Newly Registered and Carry Forward Securities | ☐Not Applicable |
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| Security Type | Security Class Title | Fee Calculation or Carry Forward Rule | Amount Registered | Proposed Maximum Offering Price Per Unit | Maximum Aggregate Offering Price | Fee Rate | Amount of Registration Fee | Carry Forward Form Type | Carry Forward File Number | Carry Forward Initial Effective Date | Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Newly Registered Securities | |||||||||||||
| Fees to be Paid | 1 | Equity | Voting common stock, par value $0.0001 per share | 457(a) | 200,000 | $ 1.30 | $ 260,000.00 | 0.0001381 | $ 35.91 | ||||
| Fees Previously Paid | 2 | Equity | Voting common stock, par value $0.0001 per share | 457(a) | 40,800,000 | $ 2.20 | $ 89,760,000.00 | $ 12,395.86 | |||||
| Carry Forward Securities | |||||||||||||
| Carry Forward Securities | |||||||||||||
| Total Offering Amounts: | $ 90,020,000.00 | $ 12,431.77 | |||||||||||
| Total Fees Previously Paid: | $ 12,395.86 | ||||||||||||
| Total Fee Offsets: | $ 0.00 | ||||||||||||
| Net Fee Due: | $ 35.91 | ||||||||||||
| Offering Note |
| 1 | Estimated solely for the purposes of calculating the registration fee pursuant to Rule 457(c) under the Securities Act of 1933, as amended, with respect to the additional 200,000 shares of the registrant's voting common stock being newly registered pursuant to this Pre-Effective Amendment, based on the average of the high and low prices of the registrant's voting common stock as quoted on The Nasdaq Capital Market on July 22, 2026 (such date being within five business days of the date that this Pre-Effective Amendment to the Registration Statement was filed with the Securities and Exchange Commission). | ||||||
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| 2 | Reflects the amount of securities, Maximum Aggregate Offering Price, and registration fee previously registered and paid in connection with 40,800,000 shares of the registrant's voting commo stock registered pursuant to the Registration Statement as originally file with the Securities and Exchange Commission on July 16, 2026. | ||||||
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| Table 2: Fee Offset Claims and Sources | ☑Not Applicable |
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| Registrant or Filer Name | Form or Filing Type | File Number | Initial Filing Date | Filing Date | Fee Offset Claimed | Security Type Associated with Fee Offset Claimed | Security Title Associated with Fee Offset Claimed | Unsold Securities Associated with Fee Offset Claimed | Unsold Aggregate Offering Amount Associated with Fee Offset Claimed | Fee Paid with Fee Offset Source | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rules 457(b) and 0-11(a)(2) | |||||||||||||
| Fee Offset Claims | |||||||||||||
| Fee Offset Sources | |||||||||||||
| Rule 457(p) | |||||||||||||
| Fee Offset Claims | |||||||||||||
| Fee Offset Sources | |||||||||||||
| Table 3: Combined Prospectuses | ☑Not Applicable |
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| Security Type | Security Class Title | Amount of Securities Previously Registered | Maximum Aggregate Offering Price of Securities Previously Registered | Form Type | File Number | Initial Effective Date | |
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