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CRNX · Current Report (Form 8-K) · Filed March 23, 2026

Crinetics Pharmaceuticals Inc — Current Report (Form 8-K)

Form
8-K
Filed
March 23, 2026
Period
Mar 17, 2026
Ticker
CRNX
Accession
0001658247-26-000020
Boardroom Alpha · Filing insights

Crinetics COO Jeff Knight resigns, effective April 10, 2026, to pursue another opportunity. His duties will be reassigned within the executive team.

About Crinetics Pharmaceuticals Inc
Market cap
$3.4B
1Y TSR
+19.7%
3Y TSR
+22.5%
Board grade
C+
Sector
Healthcare
CEO
Richard Scott Struthers
Last annual meeting: Jun 18, 2026 · View full Crinetics Pharmaceuticals Inc profile →
crnx-20260317

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
_________________________________________________________
FORM 8-K
_________________________________________________________
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
Date of Report (Date of earliest event reported): March 17, 2026
_________________________________________________________
Crinetics Pharmaceuticals, Inc.
(Exact name of Registrant as Specified in Its Charter)
_________________________________________________________
Delaware001-3858326-3744114
(State or Other Jurisdiction
of Incorporation)
(Commission File Number)(IRS Employer
Identification No.)
6055 Lusk Boulevard
San Diego, California
92121
(Address of Principal Executive Offices)(Zip Code)
Registrant’s Telephone Number, Including Area Code: (858) 450-6464
(Former Name or Former Address, if Changed Since Last Report)
_________________________________________________________
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
o    Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
o    Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
o    Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
o    Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Securities registered pursuant to Section 12(b) of the Act:
Title of each classTrading
Symbol(s)
Name of each exchange on which registered
Common Stock, par value $0.001 per shareCRNXNasdaq Global Select Market
Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).
Emerging growth company o
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. o



Item 5.02 Departure of Directors or Certain Officers; Election of Directors, Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.
On March 17, 2026, Jeff Knight notified Crinetics Pharmaceuticals, Inc. (the “Company”) of his decision to resign as Chief Development and Operating Officer of the Company, effective on or about April 10, 2026. Mr. Knight resigned to pursue another opportunity, and his resignation is not related to any disagreement with the Company on any matter relating to the Company’s operations, policies or practices. All of Mr. Knight’s managerial responsibilities and direct reports will be reassigned to other members of the executive leadership team.



SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.
Crinetics Pharmaceuticals, Inc.
Date:
March 23, 2026
By:/s/ R. Scott Struthers, Ph.D.
R. Scott Struthers, Ph.D.
President and Chief Executive Officer
(Principal Executive Officer)

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Reference

Frequently asked questions

When did Crinetics Pharmaceuticals Inc file this 8-K?
Crinetics Pharmaceuticals Inc (CRNX) filed this Current Report (Form 8-K) with the SEC on March 23, 2026. The accession number assigned by EDGAR is 0001658247-26-000020.
What does an 8-K disclose?
Form 8-K is the SEC's current-report form, used to disclose material events between periodic reports (10-K / 10-Q). Triggers include CEO/CFO departures, acquisitions, bankruptcies, earnings releases, auditor changes, changes in fiscal year, and amendments to corporate governance. Each 8-K is keyed to one or more Item numbers (1.01 through 9.01).
What is the key takeaway from this filing?
Crinetics COO Jeff Knight resigns, effective April 10, 2026, to pursue another opportunity. His duties will be reassigned within the executive team. This is Boardroom Alpha's one-line summary of the current report; see the full filing text above for the formal disclosure.
What Item codes does an 8-K cover?
An 8-K's Item codes (1.01 through 9.01) specify what kind of event is being disclosed — e.g. Item 1.01 for entering a material agreement, Item 5.02 for departure/election of directors and executive officers, Item 8.01 for other events. The Item codes for this 8-K appear in the filing text above.
Where can I find Crinetics Pharmaceuticals Inc's prior current reports on EDGAR?
The SEC EDGAR browser lists every 8-K Crinetics Pharmaceuticals Inc has filed under CIK 1658247, sortable by date. Use the "View on SEC EDGAR" link in the page header, or browse directly via https://www.sec.gov/cgi-bin/browse-edgar.
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