CLPT · Annual Report (Form 10-K) · Filed March 17, 2026

Clearpoint Neuro Inc — 10-K exhibit

clpt-ex23_1.htm

EX-23.1

Exhibit 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We consent to the inclusion or incorporation by reference of our report, dated March 17, 2026, with respect to the consolidated balance sheets of ClearPoint Neuro, Inc. (the “Company”) as of December 31, 2025 and 2024 and the related consolidated statements of operations, stockholders’ equity, and cash flows for the years then ended, in (i) the Company’s Registration Statement on Form S-8 (No. 333-183382), (ii) the Company’s Registration Statement on Form S-8 (No. 333-191908), (iii) the Company’s Registration Statement on Form S-8 (No. 333-206432), (iv) the Company’s Registration Statement on Form S-8 (No. 333-220783), (v) the Company’s Registration Statement on Form S-8 (No. 333-238907), (vi) the Company’s Registration Statement on Form S-8 No. (333-256789), (vii) the Company’s Registration Statement on Form S-8 (No. 333-265349), (viii) the Company’s Registration Statement on Form S-3 (No. 333-275476), (ix) the Company’s Registration Statement on Form S-8 (No. 333-279454), (x) the Company’s Registration Statement on Form S-8 (No. 333-290033), (xi) the Company’s Registration Statement on Form S-3 (No. 333-292733), and (xii) the Company’s Registration Statement on Form S-8 (No. 333-293317).

/s/ Cherry Bekaert LLP

Tampa, Florida

March 17, 2026

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