1 nominee · 3 ballot items.
Three proposals: (1) election of Class III director Michael Kauffman; (2) advisory (non-binding) approval of named executive officer compensation (say-on-pay); and (3) ratification of PricewaterhouseCoopers LLP as the Company’s independent registered public accounting firm for 2026.
Elect Michael Kauffman, M.D., Ph.D., as a Class III director to hold office until the 2029 annual meeting of stockholders.
A non-binding, advisory vote to approve the compensation of the Company’s named executive officers as disclosed in the proxy statement pursuant to Item 402 of Regulation S-K.
This advisory proposal asks stockholders to cast a non-binding vote approving the overall compensation of the Company’s named executive officers as disclosed in the proxy statement. Management is seeking this advisory endorsement to confirm stockholder support for its pay philosophy and program design — which relies heavily on equity (stock options) to align incentives with long-term stock price performance and includes annual cash incentives tied to corporate and individual goals. The advisory vote is non-binding, but the Board and its Compensation Committee state they will consider the voting outcome and investor feedback when making future compensation decisions. Contextually, the company underwent a major strategic reset in 2025 (sale of FibroGen International, debt repayment, and workforce reductions) and the Compensation Committee emphasizes pay-for-performance alignment, responsible equity usage, and retention of key talent during a transition to a leaner development-stage company. The proxy discloses that the Compensation Committee engaged with institutional investors and received substantive feedback used to refine disclosure and compensation practices; the company reported approximately 76% support for say-on-pay at the 2025 meeting, which the Compensation Committee viewed as broadly supportive. Management’s recommendation for a “FOR” vote is grounded in its view that compensation outcomes reflect both operational achievements in 2025 (notably the China monetization) and alignment with stockholder interests through underwater option grants and careful equity usage. For an analyst evaluating governance and investor alignment, key considerations include the advisory nature of the vote, the concentration of equity-based compensation (options-only approach), the Compensation Committee’s responsiveness to investor engagement, recent corporate actions that materially affected company size and strategy, and the potential for future adjustments informed by this and future advisory votes.
Ratify the Audit Committee’s selection of PricewaterhouseCoopers LLP as the Company’s independent registered public accounting firm for the year ending December 31, 2026.
| # | Owner | % of shares | Shares | Value |
|---|---|---|---|---|
| 1 | ARMISTICE CAPITAL, LLC | 9.88% | 400,000 | $3M |
| 2 | VANGUARD CAPITAL MANAGEMENT LLC | 3.87% | 156,607 | $1M |
| 3 | ACADIAN ASSET MANAGEMENT LLC | 2.61% | 105,585 | $716K |
| 4 | BlackRock, Inc. | 2.07% | 83,705 | $568K |
| 5 | TWO SIGMA INVESTMENTS, LP | 1.22% | 49,511 | $336K |
| 6 | HighTower Advisors, LLC | 0.98% | 39,744 | $269K |
| 7 | GEODE CAPITAL MANAGEMENT, LLC | 0.91% | 36,713 | $249K |
| 8 | UBS Group AG | 0.68% | 27,591 | $187K |
| 9 | RENAISSANCE TECHNOLOGIES LLC | 0.68% | 27,481 | $186K |
| 10 | VANGUARD FIDUCIARY TRUST CO | 0.59% | 23,942 | $162K |
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